Our L-Cysteine 500mg is available in 100 count capsules
Cysteine is a sulfur-containing non-essential amino acid that is closely related to cystine. Cystine actually contains two Cysteine molecules that are joined together. Being a non-essential amino acid means that sufficient amounts of Cysteine are formed from L-Methionine (an essential amino acid) and L-Serine via a transsulfuration reaction in the body. However, for preterm infants, Cysteine is considered to be a conditionally essential amino acid. L-Cysteine serves as a precursor for the synthesis of proteins, Glutathionine, Taurine, Coenzyme A, Biotin and Inorganic Sulfate, and also serves as a major precursor for the synthesis of the potent antioxidant Glutathione. Without adequate amounts of Glutathione in the liver, the tissues of the body can be exposed to significant oxidative stress resulting in widespread cellular damage.
L-Cysteine overview:
Cysteine is an amino acid that can be found in many proteins throughout the body. N-acetyl-L-cysteine (NAC), a modified form of cysteine, helps break down mucus and detoxify harmful substances in the body. Both cysteine and NAC have been shown to increase levels of the antioxidant glutathione.
Antioxidants are substances that scavenge free radicals, damaging compounds in the body that alter cell membranes, tamper with DNA, and even cause cell death. Free radicals occur naturally in the body, but environmental toxins (including ultraviolet light, radiation, cigarette smoking, and air pollution) can also increase the number of these damaging particles. Free radicals are believed to contribute to the aging process as well as the development of a number of health problems, including heart disease and cancer. Antioxidants such as glutathione can neutralize free radicals and may reduce or even help prevent some of the damage they cause.
Uses:
N-acetyl cysteine (NAC) offers a variety of potential therapeutic uses, particularly in the prevention or in the treatment of the following conditions:
Acetaminophen poisoning
Health care providers commonly administer oral or intravenous (IV) NAC to prevent or reduce liver and kidney damage associated with overdoses of acetaminophen (Tylenol), an over-the-counter (OTC) medication commonly used for pain or headache. Acetaminophen poisoning can occur at lower doses of the drug if someone drinks alcohol or takes certain medications that may damage the liver on a regular basis.
Heart disease
In clinical studies of people having a heart attack or those with ongoing chest pain, NAC, in combination with nitroglycerin (a drug that opens up blood vessels and improves blood flow), has been more effective than either NAC or nitroglycerin alone in reducing subsequent chest pain, heart attack, and the risk of death. However, individuals who receive both NAC and nitroglycerin may experience a severe headache. These results are promising, but further human studies are needed to confirm the safety and effectiveness of NAC for heart disease.
A large clinical study found that administering NAC after coronary bypass surgery did not improve outcomes.
Respiratory illness
A review of clinical studies also found that NAC may help dissolve mucus and improve symptoms associated with chronic bronchitis, asthma, cystic fibrosis and emphysema. Chronic smokers also may benefit from NAC supplementation. Clinical studies on large groups of people have found that NAC appears to have cancer prevention properties in people who are at risk for lung cancer.
Free radical damage is believed to contribute to the development and progression of acute respiratory distress syndrome (ARDS), a condition characterized by the rapid and progressive malfunction of the lungs. Although not all clinical studies agree, some research (laboratory and human) suggests that intravenous NAC may boost levels of glutathione and subsequently prevent and/or treat lung damage caused by ARDS. However, results of other studies have been conflicting. Further investigation is needed.
HIV/AIDS
Human immunodeficiency virus (HIV) infection is considered to be a condition of excessive oxidative stress (caused by free radicals) where the antioxidant glutathione is depleted significantly. Therefore, it is believed that supplementation with cysteine may help strengthen the immune system in those with HIV and diminish the bodily damage associated with this infection.
In one well-designed clinical study of people with HIV, those who took a daily supplement regimen including the amino acid glutamine (40 grams per day), vitamin C (800 mg), vitamin E (500 IU), beta-carotene (27,000 IU), selenium (280 mcg), and N-acetylcysteine (2400 mg) gained significantly more weight after 12 weeks than those who took placebo. Similarly, in a smaller-scale clinical study using NAC in HIV positive patients, the supplement did increase glutathione levels while a placebo did not.
These studies and others support the theory that NAC may prove to be a useful addition to conventional medical care for those with HIV. Other clinical studies, however, have shown negative results using NAC for those with HIV. Therefore, more research is needed before conclusions can be drawn about NAC supplements for this infection.
Others
Low levels of cysteine may be linked to an increased risk of cervical dysplasia (changes to the opening of the uterus that are precancerous or cancerous). Preliminary evidence also suggests that NAC supplements:
• May improve symptoms associated with Sjogren's syndrome (an autoimmune disorder characterized by dry mouth and dry eyes).
• Help enhance cognitive functioning in some individuals with Alzheimer's disease
• Prevent development of cataracts and macular degeneration
• Help treat hepatitis C when combined with standard medical treatment
• Help increase HDL cholesterol (the good kind of cholesterol)
• Help increase fertility along with fertility drugs in people with polycystic ovary disease
• Help improve outcome in children with advanced cerebral adrenoleukodystrophy, a type of leukemia
• Slow down motor impairment in amyotrophic lateral sclerosis (ALS, often called Lou Gehrig's disease which is a progressive loss of control of voluntary muscles due to destruction of nerve cells in the brain and spinal cord)
• May be useful in treating cocaine addiction. Twenty-three cocaine addicts completely or significantly reduced their use of cocaine during treatment with NAC in a small clinical study.
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